Chronic Neurological Disease
Faculty
Beth Boudreau
Boudreau’s research focuses on neuroinflammation, neuro-oncology, and non-invasive prognostic indicators for neurological disease.
C. Jane Welsh
The long-term goal of Dr. Welsh’s research is to understand how viral infections instigate the pathogenesis of neurological and autoimmune conditions. To this end, her laboratory has investigated the Theiler’s virus-induced demyelination (TVID) model of multiple sclerosis (MS) and epilepsy.
Ashok K. Shetty
Shetty’s laboratory is interested in developing clinically applicable strategies that are efficacious for enhancing brain function after injury, disease, or aging.
D. Samba Reddy
The Reddy lab is developing innovative, disease-modifying therapies for preventing the development and progression of epilepsy.
Xin Wu
Wu’s recent research in cardiovascular and neuronal systems focuses on: 1) which ion channels are activated by mechanical stress, 2) which ion channels are modulated by integrins, 3) how integrin-mediated signaling pathways modulate ion channel function and mechanotransduction in physiological and pathological conditions, 4) epilepsy study, neurosteroids and new drug development.
Roderick H. Dashwood
The Dashwood Lab examines genetic and epigenetic changes in cancer. Lab members come from diverse research backgrounds including molecular toxicology, biochemistry, cell biology, genetics, pharmacology, pharmacy, and nutrition.
Praveen Rajendran
Rajendran’s research relates to identifying novel epigenetic approaches to the treatment and prevention of colorectal cancer, where most therapeutic options are woefully ineffective.
Robert Tsai
Tsai laboratory is currently focused on developing and commercializing a novel 3-D-printed mucoadhesive patch to eradicate oral precancerous lesions; creating new diagnostic models to predict the risk of liver and oral precancerous lesions in developing into cancers; and determining the efficacy of a new class of nanomedicine in treating glioblastoma multiforme using orthotopic mouse brain tumor models.
Rahul Srinivasan
Dr. Srinivasan’s research focuses on developing a mechanistic understanding of neurodegeneration, with the goal of discovering novel strategies to treat neurodegenerative disorders
Mendell Rimer
Research in the Rimer lab centers on the molecular and cellular mechanisms underlying the formation, maintenance and pathology of synapses, the connections between nerve cells and their targets.
David J. Earnest
Research in Dr. Earnest’s laboratory employs multidisciplinary approaches to study the cellular and molecular neurobiology of cell-autonomous circadian clocks and the signal transduction pathway responsible for circadian photoentrainment.
Shameena Bake
Dr. Bake is primarily interested in stroke research. Current studies use an animal model to examine age and sex differences in recovery from stroke, focusing at the cellular level and astrocytes, and impact of alcohol consumption on stroke outcomes.
Ian Murray
Dr. Murray has been engaged in lipid and neurodegenerative disease research
for the past 30 years in both academic and industrial settings. He carried out
seminal studies in the field of protein folding involved in obesity, Parkinson's,
and Alzheimer's diseases.
Karen Newell-Rogers
Dr. Newell and her team study how individual molecular immune responses contribute to the manifestation of infectious and post-infectious chronic
inflammatory syndromes, and how a cell's energy demands, and energy strategy impact the ability of the cell to be recognized by the immune system.
Lee Shapiro
Dr. Shapiro’s lab focuses on neuroanatomical, neuropathological, neuroimmune and peripheral contributions to neurodegenerative disorders, traumatic brain injury and epilepsy.
Irtisha Singh
Dr. Singh’s team studies the pathophysiology of glioblastoma multiforme with the goal to understand dysregulation of transcriptional and co-transcriptional regulatory programs as drivers of malignancies and is interested in epigenetic and transcriptional regulatory programs.
Ursula H. Winzer-Serhan
Dr. Winzer-Serhan’s lab is interested in nicotinic receptor functions in brain development, addiction and epilepsy, and interactions with the immune system.
Hua Zhang
Dr. Zhang is interested in the Roles of bone morphogenetic protein 1 (BMP1)/tolloid-like I (TLL1) proteinases in dentinogenesis and the roles of FAM20C (family with sequence similarity 20, member C) and SIBLING (small integrin binding ligands N-linked glycoprotein) family proteins in brain homeostasis.
Dr. Gerard Toussaint